| 车次 | 始发站 | 始发时间 | 出发站 | 开车时间 | 到达站 | 到达时间 | 终点站 | 终到时间 |
| K9355 | 贵阳 | 06:05 | 贵阳 | 06:05 | 毕节 | 10:17 | 叙永北 | 12:50 |
| K9358 | 贵阳 | 06:05 | 贵阳 | 06:05 | 毕节 | 10:17 | 叙永北 | 12:50 |
| C5964 | 贵阳北 | 06:13 | 贵阳北 | 06:13 | 毕节 | 07:35 | 毕节 | 07:35 |
| C5942 | 贵阳北 | 06:59 | 贵阳北 | 06:59 | 毕节 | 07:48 | 毕节 | 07:48 |
| D1702 | 贵阳北 | 07:44 | 贵阳北 | 07:44 | 毕节 | 08:33 | 西安北 | 15:30 |
| C5944 | 贵阳北 | 07:51 | 贵阳北 | 07:51 | 毕节 | 08:52 | 毕节 | 08:52 |
| C5976 | 贵阳北 | 08:11 | 贵阳北 | 08:11 | 毕节 | 09:00 | 成都东 | 11:40 |
| D1707 | 贵阳北 | 08:17 | 贵阳北 | 08:17 | 毕节 | 09:06 | 银川 | 20:02 |
| C5982 | 贵阳北 | 08:36 | 贵阳北 | 08:36 | 毕节 | 09:25 | 成都东 | 12:18 |
| C5946 | 贵阳北 | 08:43 | 贵阳北 | 08:43 | 毕节 | 09:43 | 毕节 | 09:43 |
| C5980 | 荔波 | 07:35 | 贵阳东 | 08:50 | 毕节 | 09:38 | 成都南 | 12:06 |
| G4238 | 深圳北 | 04:36 | 贵阳东 | 08:59 | 毕节 | 09:50 | 成都东 | 13:10 |
| G5392 | 贵阳北 | 09:04 | 贵阳北 | 09:04 | 毕节 | 09:57 | 成都东 | 12:41 |
| C5988 | 贵阳北 | 09:19 | 贵阳北 | 09:19 | 毕节 | 10:37 | 毕节 | 10:37 |
| G2832 | 昆明南 | 07:00 | 贵阳北 | 09:43 | 毕节 | 10:31 | 绵阳 | 14:17 |
| D1718 | 贵阳北 | 09:49 | 贵阳北 | 09:49 | 毕节 | 10:44 | 太原南 | 21:25 |
| G8756 | 重庆西 | 08:11 | 贵阳北 | 10:23 | 毕节 | 11:11 | 重庆北 | 16:06 |
| G8757 | 重庆西 | 08:11 | 贵阳北 | 10:23 | 毕节 | 11:11 | 重庆北 | 16:06 |
| G8764 | 贵阳北 | 10:42 | 贵阳北 | 10:42 | 毕节 | 17:33 | 贵阳北 | 18:23 |
| G8765 | 贵阳北 | 10:42 | 贵阳北 | 10:42 | 毕节 | 17:33 | 贵阳北 | 18:23 |
| C5948 | 贵阳北 | 10:49 | 贵阳北 | 10:49 | 毕节 | 11:38 | 毕节 | 11:38 |
| C5864 | 花溪大学城 | 10:09 | 贵阳北 | 11:00 | 毕节 | 12:09 | 毕节 | 12:09 |
| C5972 | 贵阳北 | 12:17 | 贵阳北 | 12:17 | 毕节 | 13:21 | 毕节 | 13:21 |
| G8789 | 贵阳北 | 12:39 | 贵阳北 | 12:39 | 毕节 | 13:26 | 泸州 | 18:28 |
| G8790 | 贵阳北 | 12:39 | 贵阳北 | 12:39 | 毕节 | 13:26 | 泸州 | 18:28 |
| K9365 | 贵阳 | 13:57 | 贵阳 | 13:57 | 毕节 | 18:42 | 叙永北 | 21:38 |
| K9368 | 贵阳 | 13:57 | 贵阳 | 13:57 | 毕节 | 18:42 | 叙永北 | 21:38 |
| D6166 | 荔波 | 12:53 | 贵阳 | 14:02 | 毕节 | 15:07 | 毕节 | 15:07 |
| D6166 | 荔波 | 12:53 | 贵阳北 | 14:17 | 毕节 | 15:07 | 毕节 | 15:07 |
| D1786 | 南宁东 | 09:26 | 贵阳东 | 14:25 | 毕节 | 15:12 | 成都东 | 17:42 |
| C5866 | 花溪大学城 | 14:21 | 贵阳 | 14:58 | 毕节 | 16:19 | 毕节 | 16:19 |
| C5866 | 花溪大学城 | 14:21 | 贵阳北 | 15:19 | 毕节 | 16:19 | 毕节 | 16:19 |
| C5966 | 遵义 | 14:23 | 贵阳北 | 15:30 | 毕节 | 16:32 | 毕节 | 16:32 |
| C5967 | 遵义 | 14:23 | 贵阳北 | 15:30 | 毕节 | 16:32 | 毕节 | 16:32 |
| D1970 | 佛山西 | 10:20 | 贵阳东 | 15:40 | 毕节 | 16:27 | 西安北 | 22:58 |
| D1810 | 广州南 | 09:59 | 贵阳东 | 16:00 | 毕节 | 16:47 | 江油 | 20:27 |
| C5952 | 贵阳北 | 16:03 | 贵阳北 | 16:03 | 毕节 | 16:52 | 毕节 | 16:52 |
| D1812 | 广州南 | 10:22 | 贵阳东 | 16:10 | 毕节 | 17:14 | 绵阳 | 20:55 |
| G2185 | 杭州东 | 07:15 | 贵阳东 | 16:24 | 毕节 | 17:09 | 成都东 | 19:48 |
| G2188 | 杭州东 | 07:15 | 贵阳东 | 16:24 | 毕节 | 17:09 | 成都东 | 19:48 |
| G2189 | 上海虹桥 | 07:28 | 贵阳东 | 16:46 | 毕节 | 17:31 | 成都东 | 20:45 |
| G2192 | 上海虹桥 | 07:28 | 贵阳东 | 16:46 | 毕节 | 17:31 | 成都东 | 20:45 |
| G2804 | 昆明南 | 14:13 | 贵阳北 | 16:49 | 毕节 | 17:37 | 成都东 | 20:34 |
| G3704 | 广州南 | 12:30 | 贵阳东 | 17:07 | 毕节 | 18:11 | 成都东 | 20:52 |
| G2306 | 温州南 | 08:03 | 贵阳东 | 17:27 | 毕节 | 18:24 | 毕节 | 18:24 |
| G2307 | 温州南 | 08:03 | 贵阳东 | 17:27 | 毕节 | 18:24 | 毕节 | 18:24 |
| G2278 | 厦门北 | 08:05 | 贵阳东 | 18:07 | 毕节 | 18:58 | 成都东 | 21:58 |
| G2279 | 厦门北 | 08:05 | 贵阳东 | 18:07 | 毕节 | 18:58 | 成都东 | 21:58 |
| C5990 | 贵阳北 | 18:22 | 贵阳北 | 18:22 | 毕节 | 19:17 | 广元 | 23:32 |
| G2302 | 温州南 | 10:19 | 贵阳东 | 19:09 | 毕节 | 19:54 | 宜宾西 | 21:05 |
| G2303 | 温州南 | 10:19 | 贵阳东 | 19:09 | 毕节 | 19:54 | 宜宾西 | 21:05 |
| G8526 | 荔波 | 17:57 | 贵阳 | 19:19 | 毕节 | 20:35 | 成都东 | 23:19 |
| C5960 | 贵阳北 | 19:22 | 贵阳北 | 19:22 | 毕节 | 20:22 | 毕节 | 20:22 |
| G8526 | 荔波 | 17:57 | 贵阳北 | 19:41 | 毕节 | 20:35 | 成都东 | 23:19 |
| G2193 | 上海虹桥 | 10:48 | 贵阳东 | 19:48 | 毕节 | 20:45 | 成都东 | 23:25 |
| G2196 | 上海虹桥 | 10:48 | 贵阳东 | 19:48 | 毕节 | 20:45 | 成都东 | 23:25 |
| D6168 | 荔波 | 18:29 | 贵阳 | 19:51 | 毕节 | 21:21 | 毕节 | 21:21 |
| G2971 | 铜仁 | 18:05 | 贵阳东 | 20:04 | 毕节 | 20:55 | 成都东 | 23:37 |
| G2974 | 铜仁 | 18:05 | 贵阳东 | 20:04 | 毕节 | 20:55 | 成都东 | 23:37 |
| D6168 | 荔波 | 18:29 | 贵阳北 | 20:20 | 毕节 | 21:21 | 毕节 | 21:21 |
| G3706 | 广州南 | 15:55 | 贵阳东 | 20:56 | 毕节 | 21:42 | 宜宾西 | 22:44 |
| G4992 | 广州南 | 15:55 | 贵阳东 | 20:56 | 毕节 | 21:42 | 广元 | 01:48 |
| C5962 | 贵阳北 | 22:10 | 贵阳北 | 22:10 | 毕节 | 22:59 | 毕节 | 22:59 |
| D1862 | 广州南 | 16:41 | 贵阳北 | 22:42 | 毕节 | 23:31 | 毕节 | 23:31 |
| C5978 | 贵阳北 | 22:50 | 贵阳北 | 22:50 | 毕节 | 23:39 | 毕节 | 23:39 |